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Media Category: Clinical & Practice

Differential Diagnosis in MS, NMO-SD and MOGAD

Written by ParadigMS Foundation on .

ABSTRACT In the past 20 years, the concept of antibody mediated demyelinating disorders have emerged. These diseases, namely Aquaporin-4 (AQP4) positive neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte (MOG)- antibody associated disease (MOGAD), share common features with multiple sclerosis, but are fundamentally different in terms of pathophysiology, disease course and treatment. In this lecture we will provide a clinical, biological and imaging description of these two entities, and propose a focus on the features that helps to differentiate in between...

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Matthijs Oyaert on diagnostic tests used in the context of MS, NMO-SD, and MOGAD

Written by ParadigMS Foundation on .

BIOGRAPHY Matthijs Oyaert Matthijs Oyaert graduated as a master in drug development (pharmacy) in 2011 and master in clinical biology in 2016 at the KU Leuven and started working as a clinical biologist at the clinical laboratory of the Ghent University hospital. In the laboratory of clinical chemistry and hematology, he is responsible for a broad variety of (automated) routine clinical chemistry and immunochemistry tests and urinary test strip and particle analysis. In addition, he is involved in the laboratory diagnosis of auto-immune and neuroinflammatory diseases. During the...

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Romain Marignier on Differential Diagnosis

Written by ParadigMS Foundation on .

BIOGRAPHY Romain Marignier Prof. Romain Marignier is a neurologist (MD), professor in the Neurological Hospital of Lyon, France. His field of expertise are the neuro-inflammatory disorders of the central nervous system with a specific interest on rare disorders, namely neuromyelitis optica spectrum disorders (NMOSD) and MOG-Ab associated diseases (MOGAD). Pr Marignier is the coordinator of the French nationwide NMO and MOGAD cohorts and biobanks, NOMADMUS, set up in 2010 that includes all the French clinical experts in neuro-inflammatory disorders. Through NOMADMUS, Pr Marignier...

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Patient-reported Outcomes: Novel Examination Techniques to Uncover Disability Accumulation

Written by ParadigMS Foundation on .

Identification of progression needs new (digital) tools: •Which can monitor different symptoma domains •Which can assessment neurological function in a quantitative way •Which are sensitive enough to detect even subtle changes Patient-reported outcomes can assist using innovative instruments to detect progression from the patient perspective. Data should be collected and analyzed on one platform.

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Prognostication, high efficacy treatments and virtual care in multiple sclerosis (Accredited by EACCME)

Written by ParadigMS Foundation on .

Navigate to this page to start this elearning. This e-learning module is part of a series of 5 e-learnings created by ParadigMS on Prognostication, high efficacy treatments and virtual care in MS. Each module has a lead author and several contributors, all are neurologists with an expertise in multiple sclerosis and members of ParadigMS. You will receive an EACCME certificate upon completing the e-learning and successfully passing an exam.

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Precision Medicine in Multiple Sclerosis

Written by ParadigMS Foundation on .

Precision medicine represents the most advanced way that individual MS patients can be assessed and treated.  AUTHOR NIKOLAOS GRIGORIADISNikolaos Grigoriadis graduated from the Faculty of Medicine of the Aristotle University of Thessaloniki. He did his PhD thesis and residency in Neurology in the same institution. He has been specialized in clinical and experimental Neuroimmunology and CNS immunopathology in a number of research centers and institutions abroad. He is now Professor of Neurology at the Aristotle University of Thessaloniki and Head of the of the B’ Dept of Neurology,...

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