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Prof. Romain Marignier on Differential Diagnosis

In this 3 min interview, Prof. Romain Marignier speaks on Differential Diagnosis, key challenges differentiating between MS, NMO-SD, and MOGAD, and on related emerging technologies.


Romain Marignier

Prof. Romain Marignier is a neurologist (MD), professor in the Neurological Hospital of Lyon, France. His field of expertise are the neuro-inflammatory disorders of the central nervous system with a specific interest on rare disorders, namely neuromyelitis optica spectrum disorders (NMOSD) and MOG-Ab associated diseases (MOGAD). Pr Marignier is the coordinator of the French nationwide NMO and MOGAD cohorts and biobanks, NOMADMUS, set up in 2010 that includes all the French clinical experts in neuro-inflammatory disorders. Through NOMADMUS, Pr Marignier provided breakthrough insights in the topic regarding clinical characterization, management, and treatment of NMOSD and MOGAD, supported by major publication in high-profile journals.

Since 2017, Prof. Marignier is the head of the French referral center for rare inflammatory disorder of the central nervous system (MIRCEM), providing expertise on diagnosis and management of NMOSD and MOGAD for both patients and clinicians.

Finally, Prof. Marignier achieved a PhD on basic neurosciences in 2011 at Claude Bernard University Lyon 1 on the role of auto-antibodies in NMOSD and related diseases. He actually performs his research at INSERM unit 1028 in Lyon Neuroscience Research Centre (CRNL) on: 1. The pathophysiology of auto antibody- mediated disorders of the central nervous system with in vitro, ex vivo and animal models; 2. The development of new strategies to optimise detection of auto-antibodies (anti-AQP4, anti-MOG, anti-GFAP) for diagnosis and prognosis purpose (immunohistochemistry, flow cytometry).



  • Directors

  • Author(s)

    Prof. Romain Marignier
  • Country

  • Release Date

    March 28, 2024
  • Views


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