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Media Category: Clinical & Practice

E-learning | New diagnostic criteria for MS (Accredited by EACCME®)

Written by ParadigMS Foundation on .

The 2024 revision of the McDonald criteria introduces important advances in Multiple Sclerosis (MS) diagnosis. But how can healthcare professionals apply these updates to ensure earlier and more accurate diagnosis? This e-learning provides practical guidance on the revised criteria, including optic nerve involvement, advanced MRI biomarkers, and cerebrospinal fluid markers, helping clinicians navigate complex diagnostic scenarios and minimise the risk of misdiagnosis. Access the e-learning What does this e-learning include? Expert insights into the 2024 McDonald...

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E-learning | MRI and the implication of the new diagnostic criteria (accredited by EACCME®)

Written by ParadigMS Foundation on .

The 2024 revision of the McDonald criteria introduces important changes to improve the accuracy and timeliness of Multiple Sclerosis (MS) diagnosis. How can healthcare professionals integrate these updates into clinical practice? This e-learning provides practical insights into the updated diagnostic criteria, including the role of the optic nerve, the Central Vein Sign (CVS), and Paramagnetic Rim Lesions (PRL), helping clinicians navigate diagnostic challenges and improve patient care. Access the e-learning What does this e-learning include? Expert insights into the...

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E-learning | A practical guide: Uncovering disease progression in Multiple Sclerosis independent of relapse activity

Written by ParadigMS Foundation on .

Disease progression in Multiple Sclerosis (MS) can occur independently of relapses, making early detection and monitoring essential to improving long-term patient outcomes. But how can healthcare professionals recognise subtle signs of progression and translate emerging scientific insights into everyday clinical practice? Access the e-learning What does this e-learning include? This self-paced course, featuring 24 short videos of approximately 5-7 minutes each, includes: Expert presentations on disease progression, PIRA and the emerging concept of smouldering MS. ...

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Severe Optic Neuritis in MS: Diagnostic Challenges and Clinical Outcomes

Written by ParadigMS Foundation on .

In this clinical case lecture, Vincent van Pesch examines three cases of severe optic neuritis in young patients with Multiple Sclerosis (MS), illustrating the diversity of clinical presentations and visual outcomes. Key Insights from the Lecture: Recognise atypical presentations: Severe visual loss, optic disc edema, uveitis and retinal periphlebitis can occur in MS-related optic neuritis. Strengthen differential diagnosis: MRI, optical coherence tomography (OCT), cerebrospinal fluid analysis and antibody testing help distinguish MS from NMOSD and MOGAD. Consider early...

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MOGAD After 50 Years: Revisiting the Diagnosis of Recurrent Optic Neuritis

Written by ParadigMS Foundation on .

In this clinical case lecture, Dominique Dive explores the diagnostic challenges of recurrent optic neuritis through the case of a woman whose condition remained undiagnosed for over 50 years. Despite multiple episodes of severe visual loss and extensive investigations, the diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD) was only established following positive MOG antibody testing. Key Insights from the Lecture: Revisit longstanding diagnoses: A detailed review of the patient’s clinical history can reveal diagnostic clues, even decades after disease...

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NMOSD: Diagnostic Challenges and Treatment Decisions in a 79-Year-Old Patient

Written by ParadigMS Foundation on .

In this clinical case lecture, Thomas Scheinok presents the diagnostic and therapeutic challenges of aquaporin-4 antibody-positive Neuromyelitis Optica Spectrum Disorder (AQP4-IgG+ NMOSD) in a 79-year-old patient. Initially presenting with acute monocular vision loss, the patient developed longitudinally extensive transverse myelitis, leading to the diagnosis of NMOSD. Key Insights from the Lecture: Consider NMOSD regardless of age: Late-onset NMOSD should remain part of the differential diagnosis, even in elderly patients presenting with atypical optic neuropathy. Recognise...

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