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Media Category: Clinical & Practice

Thomas Berger: Using MRI Wisely in Multiple Sclerosis – Practical Guidance for Everyday Clinical Practice

Written by ParadigMS Foundation on .

In this short video interview, Thomas Berger explains how MRI should be used pragmatically in the diagnosis and monitoring of multiple sclerosis. Watch the interview How should MRI be used pragmatically in the diagnosis and monitoring of multiple sclerosis in everyday clinical practice? Key points discussed include: The need for MRI protocols that are practical, efficient, and accessible for the majority of patients worldwide The central role of typical morphological changes on MRI (especially T2 lesion burden) in establishing diagnosis The importance of identifying...

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ParadigMS publication in NEURON(E) journal: Translating the 2024 McDonald Criteria into Clinical Practice 

Written by ParadigMS Foundation on .

Source (journal article): NEURON, Vol. 30, #3 (2025), pp. 18–22 (Dutch). In this article, Christine Lebrun-Frenay, member of the McDonald and ECTRIMS committees and co-founder of the RIS Consortium, reviews the rationale behind the 2024 revision and discusses its practical implications, particularly in asymptomatic patients transitioning from Radiologically Isolated Syndrome (RIS) to Multiple Sclerosis (MS). This publication reflects ParadigMS’ ongoing commitment to translating evolving diagnostic frameworks into clinically relevant guidance for neurologists. Key takeaways The...

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New insights in the 2024 McDonald criteria: imaging biomarkers shaping MS diagnosis

Written by ParadigMS Foundation on .

In this keynote lecture at the Belgian MS Symposium 2025, Pietro Maggi discussed how advanced MRI biomarkers have been integrated into the upcoming 2024 revisions of the McDonald diagnostic criteria for Multiple Sclerosis. Key Insights from the Webinar: These revisions aim to improve diagnostic precision and reduce misdiagnosis, particularly in early or atypical cases. Among the most significant updates are: Optic nerve involvement — now recognized as a fifth anatomical location for demonstrating dissemination in space (DIS), supported by MRI, visual evoked potentials (VEP), and...

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Translation of 2024 MS criteria for asymptomatic individuals into clinical practice: From RIS to MS

Written by ParadigMS Foundation on .

This recording will help you refine your MS diagnostic skills with Christine Lebrun-Frenay led-insights on the 2024 McDonald criteria and practical tools for confident early detection. Key Insights from the Webinar The 2024 McDonald revision refines diagnostic clarity in Multiple Sclerosis (MS) while maintaining strong continuity with the 2017 criteria. The update aims to support earlier, more confident diagnosis, particularly for asymptomatic or preclinical cases, and to reduce over-diagnosis in patients with vascular or migraine-related MRI findings. The session highlights how...

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New diagnostic criteria for MS

Written by ParadigMS Foundation on .

Curious about what’s new in the 2024 McDonald diagnostic criteria for MS? In this expert-led session, Professors Celia Oreja-Guevara and Bassem Yamout, ParadigMS Experts, walk you through the latest updates, including optic nerve involvement, advanced imaging biomarkers, and refined strategies for diagnosing MS in complex cases.Watch now to stay current and sharpen your clinical practice. “New diagnostic criteria for MS“. Please subscribe to watch. Find out about the speakers: Prof. Celia Oreja-Guevara Prof. Bassem Yamout

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