Media Category: Pathology

In this short video interview, Gregor Brecl Jakob discusses the critical need for caution when attributing optic nerve pathology to multiple sclerosis. While optic nerve involvement is acknowledged in the diagnostic criteria, he emphasizes that optic neuritis has a broad differential diagnosis and should never be assumed to be MS-related without careful evaluation. Watch the interview Why is careful differential diagnosis essential when assessing optic nerve pathology in suspected multiple sclerosis? Gregor Brecl Jakob explains how specific clinical, imaging, and...

In this short interview, Šarlota Mesaroš discusses the clinical relevance of paramagnetic rim lesions and their growing role in the diagnostic evaluation of multiple sclerosis. Watch the interview What is the clinical value of paramagnetic rim lesions in multiple sclerosis? Šarlota Mesaroš presents a clear, practice-based overview of paramagnetic rim lesions and their relevance in the diagnosis of multiple sclerosis, drawing directly on advances in MRI imaging and current diagnostic criteria. Key points discussed include: What paramagnetic rim lesions are and why they...

In this short video interview, Šarlota Mesaroš discusses why neurologists should take an active role in interpreting MRI scans in multiple sclerosis. Watch the interview Why is it important for neurologists to personally interpret MRI scans in patients with suspected multiple sclerosis? In the interview, Šarlota Mesaroš emphasizes the critical role of neurologists’ direct involvement in MRI interpretation when evaluating patients with suspected multiple sclerosis. Key points discussed include: Why neurologists should personally review MRI scans rather than relying solely...

In this short interview, Gregor Brecl Jakob discusses the role of the optic nerve as a key anatomical site in multiple sclerosis and its growing relevance in modern diagnostic criteria. Gregor explains why formally recognizing optic nerve involvement strengthens diagnostic sensitivity, supports earlier identification of MS, and reflects a more comprehensive understanding of disease dissemination. Watch the interview In the interview, Gregor Brecl Jakob explains how incorporating optic nerve involvement into diagnostic frameworks can strengthen MS diagnosis and support earlier...

In this short video interview, Šarlota Mesaroš discusses the role of the central vein sign as an advanced MRI biomarker in multiple sclerosis. While conventional MRI remains central to MS diagnosis, susceptibility-based imaging sequences now allow clinicians to visualize the venous origin of MS lesions. Šarlota highlights how the central vein sign, incorporated into the 2024 McDonald criteria, can support diagnosis and help distinguish MS from mimicking conditions, particularly when diagnostic uncertainty remains. Watch the interview What is the central vein sign, and why is it...