Šarlota Mesaroš : Reading the MRI Yourself: Recognizing Typical Lesions in Multiple Sclerosis

In this short video interview, Šarlota Mesaroš discusses why neurologists should take an active role in interpreting MRI scans in multiple sclerosis.

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Why is it important for neurologists to personally interpret MRI scans in patients with suspected multiple sclerosis?

In the interview, Šarlota Mesaroš emphasizes the critical role of neurologists’ direct involvement in MRI interpretation when evaluating patients with suspected multiple sclerosis.

Key points discussed include:

• Why neurologists should personally review MRI scans rather than relying solely on radiology reports
• The importance of accurately identifying lesion topography in brain and spinal cord imaging
• Recognizing features that are truly characteristic of MS lesions
• The role of optic nerve imaging in appropriate clinical contexts
• How careful assessment of lesion distribution and morphology helps distinguish MS from conditions such as NMOSD and MOGAD
• Strengthening imaging literacy to improve diagnostic precision and avoid misclassification

Throughout the interview, the emphasis is on strengthening neurologists’ imaging literacy to improve diagnostic accuracy and avoid misclassification of MS and its mimics.

What advice would you give to clinicians interpreting MRI findings in early or atypical MS cases?

* Please note that all the captions were generated automatically. If they do not appear, click on CC in the navigation.

Key messages from Šarlota Mesaroš

MRI interpretation is a core clinical skill in the management of multiple sclerosis. In this interview, Šarlota Mesaroš emphasizes that neurologists should personally review brain, spinal cord, and optic nerve imaging rather than relying exclusively on written reports.

Accurate recognition of lesion morphology and topography is essential for establishing the correct diagnosis. Misinterpretation of lesion location, extent, or pattern can lead to misclassification and inappropriate management.

Overall, the discussion underscores the importance of integrating imaging expertise with clinical judgment. Strengthening neurologists’ MRI literacy enables more confident differentiation of MS from conditions such as NMOSD, MOGAD, and other inflammatory CNS disorders.

Curious to learn more about the expert behind this interview?

Visit Šarlota Mesaroš’s full biography for more insights into her expertise.

Šarlota Mesaroš

Professor of Neurology at the Faculty of Medicine, University of Belgrade, Serbia
Consultant neurologist at the Department for immune-mediated CNS disorders, Neurology
Clinic, University Clinical Center of Serbia, Belgrade, Serbia.
Main field of research interest is diagnosis and treatment of MS and related disorders and
neuroimaging.
Vice-president of Serbian Neuroimmunology Society.

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