Media Category: Treatments

This lecture reviews the clinical use of sphingosine-1-phosphate (S1P) receptor modulators in Multiple Sclerosis, with a focus on their mechanisms of action, receptor selectivity, pharmacokinetics, and safety considerations. Magd Zakaria discusses how differences in half-life, metabolism, and receptor targeting influence efficacy, adverse events, monitoring requirements, and treatment sequencing, including switching strategies and special populations such as women planning pregnancy. Key Insights from the Lecture: S1P receptor modulators exert their therapeutic effect by...

In this keynote from Athens, medical cannabis is discussed as an emerging option for neuropathic pain and spasticity, with a particular focus on people living with multiple sclerosis. Evidence from clinical trials, large real-world cohorts and national prescribing data is reviewed, together with practical experience from a high-volume pain clinic. The presentation highlights how medical cannabis may reduce pain, spasticity and opioid use, while underlining current gaps in guidelines, regulatory hurdles and the need for careful titration and follow-up. Key Insights from the...

Immune reconstitution therapies are reshaping modern MS management, offering periods of lasting disease control without continuous immunosuppression. In this thought-provoking session, Prof. Patrick Vermersch, leading MS clinician and clinical trial expert, examines how IRTs work in real clinical practice, what drives long-term success, and how to navigate risks, patient selection, and treatment timing. Drawing on decades of research and clinical experience, Prof. Vermersch provides a clear and clinically meaningful framework for understanding cladribine, alemtuzumab, HSCT, and...

In this educational session, Prof. Celia Oreja-Guevara explores the crucial role of microglia in multiple sclerosis and how our evolving understanding of these resident immune cells is reshaping approaches to disease monitoring and treatment. Professor Oreja-Guevara discusses how microglial activation contributes to lesion development, chronic inflammation, and disability progression, while highlighting emerging therapeutic strategies targeting neuroinflammation. With clear clinical relevance and a forward-looking perspective, this presentation is ideal for neurologists and clinicians...