Skip to main content

Media Category: Treatments

NMOSD Panel Discussion: Pathophysiology, Monitoring, and Treatment Challenges

Written by ParadigMS Foundation on .

This expert panel discussion explores the current challenges in understanding and managing neuromyelitis optica spectrum disorder (NMOSD). Bringing together clinical perspectives, the conversation highlights gaps in pathophysiology, limitations in monitoring tools, and ongoing uncertainties in long-term treatment strategies. Despite advances in biomarkers and therapies, real-world decision-making remains largely driven by clinical experience. Key Insights from the Lecture: Antibodies alone are not sufficient to cause disease Clinical context remains essential T cells play a...

Continue reading

Multiple Sclerosis and pregnancy: from planning to postpartum

Written by ParadigMS Foundation on .

Family planning is a central concern for women living with multiple sclerosis, as the disease often affects patients during their reproductive years. Questions around pregnancy, treatment safety, and postpartum relapse risk require careful, individualized planning. With the right multidisciplinary approach and treatment strategies, pregnancy can be safely managed while minimizing risks for both mother and child. Key Insights from the Lecture: Family planning is a key concern in MS care Pregnancies are not always planned Planning pregnancy reduces risks Multidisciplinary...

Continue reading

The clinical management of NMOSD

Written by ParadigMS Foundation on .

Neuromyelitis optica spectrum disorder (NMOSD) is a rare but severe relapsing disease of the central nervous system, characterized by attacks that lead to cumulative disability. Unlike multiple sclerosis, progression is not continuous but driven by relapses, making early diagnosis and rapid treatment essential. Advances in biomarkers, classification, and targeted therapies are reshaping how clinicians approach NMOSD management. Key Insights from the Lecture: NMOSD is a rare but globally variable disease Disability is driven by relapses, not progression Aquaporin-4 antibodies...

Continue reading

The Role of Microglia in Multiple Sclerosis: Implications for Treatment with Bruton’s Tyrosine Kinase Inhibitors

Written by ParadigMS Foundation on .

Microglia are increasingly recognised as central regulators of neuroinflammation in Multiple Sclerosis (MS). Beyond their traditional classification, advances in molecular biology have revealed a spectrum of functional states that influence both tissue damage and repair. This lecture provides a concise overview of microglial biology in MS and explores how emerging therapeutic strategies, particularly Bruton tyrosine kinase (BTK) inhibitors, may modulate these cells to impact disease progression. Key Insights from the Lecture: Microglia as central orchestrators of CNS immunity: Microglia...

Continue reading

Prognostic Factors for Evaluation of MS Therapy in Treatment Naive Patients

Written by ParadigMS Foundation on .

Magd Zakaria presented a clinically oriented approach to integrating prognostic factors into early treatment decision-making in Multiple Sclerosis (MS). Building on current evidence and international guidelines, this keynote addresses a central question in MS management: how to balance early use of high-efficacy therapies with individual disease activity, patient characteristics, and healthcare system constraints. Key Insights from the Lecture: Disability progression in MS is primarily driven by progression independent of relapse activity (PIRA), which begins early in the disease...

Continue reading

The Clinical Management of NMOSD in Belgium

Written by ParadigMS Foundation on .

Neuromyelitis optica spectrum disorder (NMOSD) is a rare but severe neuroinflammatory disease requiring rapid diagnosis and prompt treatment to prevent irreversible disability. In this expert-led webinar, Vincent van Pesch explores the latest advances in NMOSD diagnosis and management, with a particular focus on clinical practice in Belgium. The webinar is introduced and moderated by Melissa Cambron. The session covers diagnostic red flags, imaging features, antibody testing, and evolving therapeutic strategies that are reshaping patient care. Learning Objectives After watching...

Continue reading

FAQs

Is ParadigMS for free?

Yes, a ParadigMS subscription is free for healthcare practitioniers. 

Do subscriptions auto-renew?
Your subscription will automatically renew on yearly basis. If you cancel your plan, it will not renew at the end of your subscription cycle. 
I am a representative from industry, can I subscribe?

Free subscriptions to ParadigMS are reserved for healthcare practitioners. If you are a representative of the industry please contact us on learning@paradigms.foundation and we would advise you how to get the access to the material. 

What happens if I subscribe as a HCP if I am not?
If you subscribe as a healthcare practitioner and it is proven that you are not a healthcare practitioner, we will cancel your subscription immediately. 
I am a patient, can I subscribe?

ParadigMS is designed specifically for healthcare practitioners, with content and language tailored to their professional needs. While patients cannot subscribe directly, we encourage you to consult your healthcare provider for relevant insights and updates that may benefit you.

Why should I subscribe to ParadigMS's e-platform?

Subscribing to ParadigMS’s e-platform gives you access to up-to-date information and valuable learning materials on multiple sclerosis and NMO, along with expert insights and the latest innovations in the field. It’s an essential resource for staying informed and enhancing your knowledge in MS care.

How can I cancel my subscription?
You can cancel your subscription in your account settings. 
Can I financially support ParadigMS?

Yes, you can financially support ParadigMS! We welcome donations to help us continue our mission of advancing multiple sclerosis education and research. Your contribution directly supports the creation of educational resources, expert discussions, and innovative projects in MS care. Visit our donation page to learn more about how you can make a difference: ParadigMS Donate.