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MRI and the implications of the new diagnostic criteria

Explore how the revised MS diagnostic criteria enhance accuracy and enable earlier diagnosis, and learn how MRI biomarkers are reshaping clinical decision-making.

This webinar provides an expert overview of the revised diagnostic criteria for Multiple Sclerosis (MS), with a specific focus on their implications for magnetic resonance imaging (MRI) in clinical practice.

Building on the 2017 framework, the updated criteria aim to improve diagnostic specificity while enabling earlier and more accurate identification of MS. The session reviews the key changes, including the introduction of new topographies and MRI biomarkers, and discusses how these elements can be integrated into routine clinical workflows.

Through expert insights and clinical examples, the webinar highlights how MRI continues to play a central role, not only in diagnosis, but also in prognosis and disease monitoring, supporting more informed and timely clinical decision-making.

Learning Objectives

After watching this webinar, participants will be able to:

  • Understand the key updates in the revised MS diagnostic criteria and their clinical rationale
  • Identify the role of MRI in demonstrating dissemination in space and time under the new framework
  • Recognise the added value of new MRI biomarkers, including the central vein sign (CVS) and paramagnetic rim lesions (PRL)
  • Integrate optic nerve assessment into the diagnostic process using MRI, optical coherence tomography (OCT), or visual evoked potentials (VEP)
  • Apply the updated criteria in complex or ambiguous clinical scenarios, including radiologically isolated syndrome (RIS) and older patients
  • Differentiate MS from key mimics such as Neuromyelitis Optica Spectrum Disorder (NMOSD) and Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD) using imaging features

Please subscribe to watch.

Find out more about the speakers:

Co-CEO of the Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), a professor at the University of Basel, and a senior consultant neurologist at the University Hospital of Basel




Vice Chair of Neurology and Head of Multiple Sclerosis Center at the University Hospital San Carlos, Madrid


Sponsor

This educational material is funded with ParadigMS own funds.


Media

Details

  • Directors

    ParadigMS
  • Author(s)

    Cristina Granziera and Celia Oreja-Guevara
  • Country

    Switzerland and Spain
  • Release Date

    March 16, 2026
  • Views

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