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The role of Microglia in Multiple Sclerosis. Module 4 – Microglia as a target for the treatment of MS

A common theme throughout many of the sections in the e-learning is the prominent role played by brain-resident microglia in multiple sclerosis (MS). This module, authored by Prof. Patrick Vermersch, will discuss how current MS treatments reduce MS relapse activity and acute inflammation, but how the activation of innate immune cells (i.e. microglia) in the brain contributes to ongoing disability progression that is not related to relapses. Curious to learn more?   Enroll now With thanks to our sponsor who supports this e-learning without any involvement in the elaboration...

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The role of Microglia in Multiple Sclerosis. Module 2 – Clinical progression and the relation with innate immune cells

This e-learning module covers the topic of clinical progression and the relation with innate immune cells. Unlike the historical interpretation, evidence now suggests that all phenotypes lie on a multiple sclerosis continuum, and that acute and chronic inflammation are present to different extents in each form of MS. This module, authored by Professor Carlo Pozzilli, MD PhD, digs into the pathophysiology of MS to explain the MS continuum and how the activation of microglia in the brain and subsequent induction of neurodegenerative processes relate to that.   Curious to learn more?   Enroll...

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Expert meeting 18th of March Virtual

ParadigMS board members meet virtually in March 18th, 2023. At the Expert Meetings, experts peer review each others educational slide decks with the objective to publish educational materials for clinical neurologists and nurses on behalf of ParadigMS.The following “hot topics” were on agenda. Paediatric Multiple Sclerosis (Lead author: Melinda Magyari) Cerebrospinal fluid (CSF) in the diagnosis of Multiple Sclerosis (Lead author: Florian Deisenhammer) Cognition in Multiple Sclerosis: a marker of silent progression (Lead author: Carlo Pozzilli) The presentations were followed...

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