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New publication by ParadigMS Experts: Navigating generics, biosimilars, and NBCDs in MS

ParadigMS Foundation

By ParadigMS Foundation

April 30, 2025

We’re proud to share a recent publication authored by ParadigMS experts, now featured in the European Journal of Neurology:
“Generics, biosimilars and follow‐on non‐biologic complex drugs for Multiple Sclerosis: A narrative review of the regulatory and clinical implications for European neurologists.”

The review examines the growing presence of generics, biosimilars, and follow-on non-biologic complex drugs (NBCDs) in multiple sclerosis care, outlining the regulatory landscape and the practical implications for clinical practice in Europe.

Highlights include:

  • Clear distinctions between the different types of alternatives
  • Regulatory inconsistencies and their impact on prescribing
  • Key concerns around substitution and patient safety
  • The neurologist’s role in ensuring responsible integration of these options

This expert-authored review emphasizes the need for harmonized guidance and robust monitoring as these therapies become more widely used.

Read more

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