Rodica Bălaşa on Cerebrospinal Fluid as a diagnostic window in Multiple Sclerosis
Why does cerebrospinal fluid (CSF) remain an important tool in the diagnosis of multiple sclerosis, even with advances in imaging?
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In the interview, Rodica Bălaşa explains the ongoing importance of cerebrospinal fluid (CSF) evaluation in multiple sclerosis, emphasizing its role as a window into the brain’s pathological processes.
Key points discussed include:
- The evolving role of CSF analysis in the diagnosis of multiple sclerosis
- Why CSF remains relevant despite advances in imaging and other non-invasive tools
- Its position within the 2024 McDonald criteria
- When CSF assessment becomes necessary in clinical practice
- The importance of a balanced, stepwise diagnostic approach
How do you envision the role of CSF evolving in the next generation of diagnostic frameworks?
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Key messages from Rodica Bălaşa
Cerebrospinal fluid remains an important diagnostic tool in multiple sclerosis, offering direct insight into underlying autoimmune activity. In this interview, Rodica Bălaşa highlights its continued relevance within modern diagnostic frameworks.
Despite advances in non-invasive techniques, CSF analysis still plays a crucial role in selected patients when clinical and imaging findings alone are insufficient. Rather than a routine first-line test, it serves as a targeted and complementary investigation that strengthens diagnostic confidence.
Overall, the discussion reinforces a pragmatic, stepwise approach, prioritizing non-invasive assessments while recognizing that CSF remains indispensable when additional evidence is required.
Curious to learn more about the expert behind this interview?
Visit Rodica Bălaşa’s full biography for more insights into her expertise.

Rodica Bălaşa
Professor of Neurology at the University of Medicine, Pharmacy, Sciences and Technology „George Emil Palade” of Targu Mures (UMFST), Romania
Head of the Neurology 1 Clinic, Emergency Clinical County Hospital of Mures, Romania
Main field of research interest is the diagnosis and management of multiple sclerosis, cerebrospinal fluid biomarkers, and neuroimaging.
Active contributor to the development of diagnostic criteria and innovative approaches in MS care.