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Prof. Nikolaos Grigoriadis on immunopathology of NMOSD

“NMOSD is a true astrocytopathy,” says Prof. Nikolaos Grigoriadis, as he outlines the immune mechanisms behind this distinct and highly targeted disease process.

In this focused interview from EAN 2025, Prof. Nikolaos Grigoriadis unpacks the immunopathological hallmarks of neuromyelitis optica spectrum disorder (NMOSD). He discusses how aquaporin-4 antibodies trigger astrocyte injury, the role of complement activation, and why NMOSD is now recognised as a distinct astrocytopathy—shaping the development of highly targeted therapies.

“Immunopathology of NMOSD”

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Details

  • Directors

    ParadigMS

  • Author(s)

    Nikolaos Grigoriadis

  • Country

    Greece

  • Release Date

    July 13, 2025

  • Views

    805

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