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Media Category: Patient Care

Managing MS in Individuals Aged 55 and Above 

Written by ParadigMS Foundation on .

Key takeawaysAging and Disease Progression: MS in older adults often shifts from a relapsing to a progressive form, with compartmentalized inflammation and microglial activation playing a central role. Immunosenescence Considerations: Aging impacts immune function, increasing the risk of infections, especially with prolonged immunosuppressive therapy, necessitating a careful benefit-risk assessment in older patients. Treatment Efficacy Variability: Many DMTs show reduced efficacy in older MS patients, emphasizing the importance of individualized treatment plans based on age and disease stage. DMT...

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Prof. Patrick Vermersch on the topic of Multiple Sclerosis in Older Age

Written by ParadigMS Foundation on .

“What is particular to the immune system at older age?”* Please note that all the captions were generated automatically. If they do not appear, click on CC in the navigation.Interested in the next interview question?“Do you have recommendations for clinicians treating MS patient at older age?” Log-in or subscribe.Curious to learn more about the expert behind this interview? Visit Patrick Vermersch’s full biography for more insights into her expertise.Meet the Expert

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Beyond EDSS: How to monitor disease progression in MS

Written by ParadigMS Foundation on .

Key takeawaysLimitations of EDSS – The EDSS alone may not capture the full scope of MS progression, especially in cases where deterioration occurs independently of relapses (PIRA). Smoldering MS – MS can progress silently, with neurodegeneration happening beneath the surface, even when clinical symptoms seem stable. This requires a broader monitoring strategy. Multimodal Monitoring – Effective disease monitoring should go beyond neurological exams, integrating:Clinical assessments and patient-reported outcomes (PROs) Imaging techniques, such as MRI biomarkers and advanced neuroimaging Biomarkers...

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Prof. Jelena Drulovic on Multiple Sclerosis in the Balkan region

Written by ParadigMS Foundation on .

“How is the treatment landscape of people with Multiple Sclerosis in Serbia and other countries of the Balkan region?”* Please note that all the captions were generated automatically. If they do not appear, click on CC in the navigation.Interested in the next interview question? “How can organisations such as ParadigMS support clinicians in the Balkan region?” Log-in or subscribe.Curious to learn more about the expert behind this interview? Visit Jelena Drulovic’s full biography for more insights into her expertise.Meet the Expert

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Paediatric onset multiple sclerosis

Written by ParadigMS Foundation on .

BIOGRAPHYMELINDA MAGYARI Melinda Magyari is the director of The Danish Multiple Sclerosis Registry (link: www.dmsr.dk/) and a consultant neurologist at the Danish Multiple Sclerosis Center (COI). Her major research area is in multiple sclerosis and other inflammatory disorders of the central nervous system with a special interest in the changing epidemiology and gender differences. Using nationwide population-based data sources her research addresses questions on comorbidities, reproductive issues, risk factors and socioeconomic consequences in multiple sclerosis. She is involved in pharmacoepidemiological...

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COVID19 experiences and Virtual MS-care

Written by ParadigMS Foundation on .

24th June 2021, Sixth ParadigMS Symposium,The ParadigMS Foundation and the Belgian Study Group for Multiple Sclerosis (BSGMS) organised their annual symposium. Here you can review the full keynote on Innate Immunity and the Role of Microglia in MS.ABSTRACTCOVID-19 and MS The COVID-19 pandemic has obliged us to change the way things are done in many aspects of our lives. When it comes to multiple sclerosis (MS), neurologists have been forced to reinvent the way MS patients are managed, with fewer hospital visits and telemedicine now commonplace. Vaccinating patients against SARS-Cov-2 will provide...

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