Paediatric Multiple Sclerosis

Pediatric-onset Multiple Sclerosis is rare, but early recognition and appropriate treatment are critical. Explore expert guidance on differential diagnosis, biomarkers, disease progression and treatment strategies in children with MS.

Pediatric-onset Multiple Sclerosis (MS) accounts for a small proportion of MS cases, yet its early onset can lead to substantial disability at a young age. Accurate diagnosis can also be challenging, particularly when distinguishing MS from Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD), acute disseminated encephalomyelitis (ADEM) and other inflammatory or genetic disorders.

In this webinar, Thaís Armangué and Carlo Pozzilli, moderated by Valeria Pozzilli, review the clinical course of pediatric-onset MS and discuss practical approaches to differential diagnosis, biomarkers, imaging and treatment. The session also examines evolving evidence supporting early treatment and the role of high-efficacy therapies in pediatric MS.

Key Insights from the Lecture:

After this webinar, participants should be able to:

• Describe the epidemiology and natural history of pediatric-onset Multiple Sclerosis (MS).
• Recognise key clinical and imaging features that help differentiate pediatric MS from MOGAD, ADEM and other mimicking conditions.
• Discuss the role and limitations of MOG-IgG, oligoclonal bands and serum neurofilament light chain in diagnosis and disease monitoring.
• Identify clinical and imaging factors associated with disease activity and future disability.
• Review current treatment strategies for pediatric MS, including oral therapies and high-efficacy monoclonal antibodies.
• Apply an individualised approach to treatment selection based on disease activity, prognosis, safety and patient-related factors.

“Pediatric Multiple Sclerosis: Diagnosis, Disease Course and Treatment”

Please subscribe to watch.

Log-in or subscribe

About the speakers:

Professor of Clinical Neuroscience at University of Rome “La Sapienza”

Head of the Department and attending in the Paediatric Neuroimmunology Unit at SJD Barcelona Children’s Hospital

Neurologist and researcher, Queen Square MS Centre, UCL Queen Square Institute of Neurology, University College London, United Kingdom

Funding

This webinar was organized with the financial support of Roche. Roche has not been involved in the elaboration of the presentations.

We value your opinion.

or a colleague?

How likely are you to recommend this material to a friend or colleague?

Selected Value: 1

Give a score from 1 (= not at all likely) to 10 (extremely likely)

Tell us what you think or ask a question to the expert.

Give your opinion on the quality of the material and send us your comments, questions or feedback. Where relevant, we'll liaise with the Expert and get back to you.

Email

If you have submitted a question above, leave your email so we can get back to you.

Submit