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Media Type: Recorded Webinars

Panel discussion: How Healthcare Systems Impact Treatment Choice in Multiple Sclerosis

Written by ParadigMS Foundation on .

Healthcare systems play a central role in shaping access to Multiple Sclerosis (MS) care. In this international expert discussion, neurologists explore how national healthcare policies, treatment pathways and multidisciplinary approaches influence clinical practice and patient outcomes. This Paradigms Foundation webinar brings together international MS experts to discuss how healthcare systems influence the management of Multiple Sclerosis. Drawing on experiences from Egypt, Denmark, Germany, Greece and Serbia, the panel explores differences in treatment access, healthcare...

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Optic Neuritis as a window to the brain: MRI and functional VEP

Written by ParadigMS Foundation on .

This lecture examines optic neuritis as both a clinical syndrome and a valuable model for understanding inflammatory and neurodegenerative processes in Multiple Sclerosis. Drawing on extensive clinical experience and research, Jette Lautrup Frederiksen explores how advances in diagnostic techniques have improved the identification, classification and monitoring of optic neuritis. Key Insights from the Lecture: Recognise optic neuritis as a heterogeneous syndrome: Optic neuritis may occur in MS, NMOSD, MOGAD and other conditions, making accurate differential diagnosis essential. ...

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Severe Optic Neuritis in MS: Diagnostic Challenges and Clinical Outcomes

Written by ParadigMS Foundation on .

In this clinical case lecture, Vincent van Pesch examines three cases of severe optic neuritis in young patients with Multiple Sclerosis (MS), illustrating the diversity of clinical presentations and visual outcomes. Key Insights from the Lecture: Recognise atypical presentations: Severe visual loss, optic disc edema, uveitis and retinal periphlebitis can occur in MS-related optic neuritis. Strengthen differential diagnosis: MRI, optical coherence tomography (OCT), cerebrospinal fluid analysis and antibody testing help distinguish MS from NMOSD and MOGAD. Consider early...

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MOGAD After 50 Years: Revisiting the Diagnosis of Recurrent Optic Neuritis

Written by ParadigMS Foundation on .

In this clinical case lecture, Dominique Dive explores the diagnostic challenges of recurrent optic neuritis through the case of a woman whose condition remained undiagnosed for over 50 years. Despite multiple episodes of severe visual loss and extensive investigations, the diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD) was only established following positive MOG antibody testing. Key Insights from the Lecture: Revisit longstanding diagnoses: A detailed review of the patient’s clinical history can reveal diagnostic clues, even decades after disease...

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NMOSD: Diagnostic Challenges and Treatment Decisions in a 79-Year-Old Patient

Written by ParadigMS Foundation on .

In this clinical case lecture, Thomas Scheinok presents the diagnostic and therapeutic challenges of aquaporin-4 antibody-positive Neuromyelitis Optica Spectrum Disorder (AQP4-IgG+ NMOSD) in a 79-year-old patient. Initially presenting with acute monocular vision loss, the patient developed longitudinally extensive transverse myelitis, leading to the diagnosis of NMOSD. Key Insights from the Lecture: Consider NMOSD regardless of age: Late-onset NMOSD should remain part of the differential diagnosis, even in elderly patients presenting with atypical optic neuropathy. Recognise...

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Clinical Aspects of Optic Neuritis

Written by ParadigMS Foundation on .

Diagnosing optic neuritis can be challenging, particularly when patients present with atypical symptoms or inconclusive imaging results. In this keynote, Axel Petzold introduces a practical, step-by-step approach to diagnosing and classifying optic neuritis. Through real-world clinical cases, he explains how symptoms such as eye pain and visual loss can be assessed alongside optical coherence tomography (OCT), magnetic resonance imaging (MRI), and antibody testing. The session explores the diagnostic differences between optic neuritis associated with multiple sclerosis (MS),...

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