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Prof. Bart Van Wijmeersch on subtle progression in MS and MS prognosis

Written by ParadigMS Foundation on .

BIOGRAPHY Bart Van Wijmeersch Bart Van Wijmeersch is a neurologist specialized in Multiple Sclerosis. He is medical director of the Rehabilitation and MS Center in Pelt where he leads the multidisciplinary MS-team. Furthermore, he is an associate professor of Neurology at the University of Hasselt, affiliated with the Biomedical Institute, where he’s involved in pre-clinical as well as the clinical research on MS at the biomedical institute (BIOMED). He has a supporting role in all the immunological research on blood- and CSF samples of persons with MS and in EAE-animal models, as...

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Differential Diagnosis in MS, NMO-SD and MOGAD

Written by ParadigMS Foundation on .

ABSTRACT In the past 20 years, the concept of antibody mediated demyelinating disorders have emerged. These diseases, namely Aquaporin-4 (AQP4) positive neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte (MOG)- antibody associated disease (MOGAD), share common features with multiple sclerosis, but are fundamentally different in terms of pathophysiology, disease course and treatment. In this lecture we will provide a clinical, biological and imaging description of these two entities, and propose a focus on the features that helps to differentiate in between these...

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Dr. Matthijs Oyaert – Lecture on Antibodies in Focus Advancements in Diagnosing NMO and MOG-related CNS Disorders

Written by ParadigMS Foundation on .

ABSTRACT Over the last decade, knowledge of antibodies linked to inflammatory disorders of the central nervous system, including forms of neuromyelitis optica (NMO) spectrum disorders, acute disseminated encephalomyelitis (ADEM), optic neuritis and transverse myelitis, has significantly reshaped the landscape of the diagnosis and clinical care. Notably, highly specific antibody assays have become an integral part of clinical decision making and include antibodies directed against the aquaporin-4 and anti–myelin oligodendrocyte glycoprotein (MOG).Various assays have been developed to...

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Dr. Matthijs Oyaert on diagnostic tests used in the context of MS, NMO-SD, and MOGAD

Written by ParadigMS Foundation on .

BIOGRAPHY Matthijs Oyaert Matthijs Oyaert graduated as a master in drug development (pharmacy) in 2011 and master in clinical biology in 2016 at the KU Leuven and started working as a clinical biologist at the clinical laboratory of the Ghent University hospital. In the laboratory of clinical chemistry and hematology, he is responsible for a broad variety of (automated) routine clinical chemistry and immunochemistry tests and urinary test strip and particle analysis. In addition, he is involved in the laboratory diagnosis of auto-immune and neuroinflammatory diseases. During the...

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