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Media Category: Quality of Life

Managing MS in Individuals Aged 55 and Above 

Written by ParadigMS Foundation on .

Key takeawaysAging and Disease Progression: MS in older adults often shifts from a relapsing to a progressive form, with compartmentalized inflammation and microglial activation playing a central role. Immunosenescence Considerations: Aging impacts immune function, increasing the risk of infections, especially with prolonged immunosuppressive therapy, necessitating a careful benefit-risk assessment in older patients. Treatment Efficacy Variability: Many DMTs show reduced efficacy in older MS patients, emphasizing the importance of individualized treatment plans based on age and disease stage. DMT...

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Prof. Patrick Vermersch on the topic of Multiple Sclerosis in Older Age

Written by ParadigMS Foundation on .

“What is particular to the immune system at older age?”* Please note that all the captions were generated automatically. If they do not appear, click on CC in the navigation.Interested in the next interview question?“Do you have recommendations for clinicians treating MS patient at older age?” Log-in or subscribe.Curious to learn more about the expert behind this interview? Visit Patrick Vermersch’s full biography for more insights into her expertise.Meet the Expert

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Beyond EDSS: How to monitor disease progression in MS

Written by ParadigMS Foundation on .

Key takeawaysLimitations of EDSS – The EDSS alone may not capture the full scope of MS progression, especially in cases where deterioration occurs independently of relapses (PIRA). Smoldering MS – MS can progress silently, with neurodegeneration happening beneath the surface, even when clinical symptoms seem stable. This requires a broader monitoring strategy. Multimodal Monitoring – Effective disease monitoring should go beyond neurological exams, integrating:Clinical assessments and patient-reported outcomes (PROs) Imaging techniques, such as MRI biomarkers and advanced neuroimaging Biomarkers...

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Paediatric onset multiple sclerosis

Written by ParadigMS Foundation on .

BIOGRAPHYMELINDA MAGYARI Melinda Magyari is the director of The Danish Multiple Sclerosis Registry (link: www.dmsr.dk/) and a consultant neurologist at the Danish Multiple Sclerosis Center (COI). Her major research area is in multiple sclerosis and other inflammatory disorders of the central nervous system with a special interest in the changing epidemiology and gender differences. Using nationwide population-based data sources her research addresses questions on comorbidities, reproductive issues, risk factors and socioeconomic consequences in multiple sclerosis. She is involved in pharmacoepidemiological...

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Quality of Life of Patients with MS: The Ideal Outcome

Written by ParadigMS Foundation on .

MONA ALKHAWAJAHDr. Mona Alkhawajah is currently a Consultant Neurologist at the Neurosciences Department of King Faisal Specialist Hospital and Research Center, Riyadh (KFSHRC-R), and is an Assistant Professor at Al Faisal University. . She has been the Program Director of the Neurology Residency Training Program at KFSHRC-R for almost 5 years. Dr. Mona Alkhawajah received her Medical Degree from King Saud University, Riyadh. She then pursued her residency training in Neurology at KFSHRC-R. After obtaining her Saudi Board in Neurology, she completed her Fellowship in Neuroimmunology at the University...

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Quality of life of patients with MS: the ideal outcome

Written by ParadigMS Foundation on .

17th of March 2016, first ParadigMS Symposium. The ParadigMS Foundation and the Belgian Study Group for Multiple Sclerosis (BSGMS) organised an interactive learning and networking experience. Here you can review one of the three lectures that were on the agenda: Quality of life of patients with MS: the ideal outcome.ABSTRACTWhen you look at the definition of paradigms you can highlight one word and that is care. Dr. Lysandropoulos wants to talk with all kind of care givers because MS is an important example of a disease in which you need a multi-disciplinary approach.Why do we care about our...

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