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Media Category: NMO

New diagnostic criteria in MS: The evolving role of biomarkers in Multiple Sclerosis

Written by ParadigMS Foundation on .

This expert panel discussion explores the current challenges in understanding and managing neuromyelitis optica spectrum disorder (NMOSD). Bringing together clinical perspectives, the conversation highlights gaps in pathophysiology, limitations in monitoring tools, and ongoing uncertainties in long-term treatment strategies. Despite advances in biomarkers and therapies, real-world decision-making remains largely driven by clinical experience. Key Insights from the Lecture: Neurofilaments and GFAP are not specific to Multiple Sclerosis and should not replace established diagnostic...

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Magd Zakaria: Recognising Typical and Atypical Presentations in Multiple Sclerosis

Written by ParadigMS Foundation on .

Watch the interview Magd Zakaria discusses the clinical features that can help distinguish typical presentations of Multiple Sclerosis from red flags suggestive of alternative demyelinating disorders. Visual, spinal cord and brainstem syndromes are among the most common clinical presentations at the onset of Multiple Sclerosis (MS), often occurring as a clinically isolated syndrome (CIS). In this interview, Magd Zakaria reviews the characteristic features of these presentations and highlights findings that are atypical for MS. He explains how symptom severity, bilateral involvement,...

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NMOSD Panel Discussion: Pathophysiology, Monitoring, and Treatment Challenges

Written by ParadigMS Foundation on .

This expert panel discussion explores the current challenges in understanding and managing neuromyelitis optica spectrum disorder (NMOSD). Bringing together clinical perspectives, the conversation highlights gaps in pathophysiology, limitations in monitoring tools, and ongoing uncertainties in long-term treatment strategies. Despite advances in biomarkers and therapies, real-world decision-making remains largely driven by clinical experience. Key Insights from the Lecture: Antibodies alone are not sufficient to cause disease Clinical context remains essential T cells play a...

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The clinical management of NMOSD

Written by ParadigMS Foundation on .

Neuromyelitis optica spectrum disorder (NMOSD) is a rare but severe relapsing disease of the central nervous system, characterized by attacks that lead to cumulative disability. Unlike multiple sclerosis, progression is not continuous but driven by relapses, making early diagnosis and rapid treatment essential. Advances in biomarkers, classification, and targeted therapies are reshaping how clinicians approach NMOSD management. Key Insights from the Lecture: NMOSD is a rare but globally variable disease Disability is driven by relapses, not progression Aquaporin-4 antibodies...

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The immunopathological hallmarks of neuromyelitis optica spectrum desorder (NMOSD)

Written by ParadigMS Foundation on .

Nikolaos Grigoriadis presents a keynote lecture on the pathophysiology of Neuromyelitis Optica Spectrum Disorder (NMOSD), focusing on the immunological mechanisms underlying disease activity. The session provides clinically relevant insights into how these mechanisms translate into relapse patterns and therapeutic targets. Key Insights from the Lecture: NMOSD is a relapse-driven disease, with disability primarily resulting from acute attacks rather than progressive mechanisms Anti-aquaporin-4 antibodies are present in the majority of patients and play a central pathogenic role...

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The Clinical Management of NMOSD in Belgium

Written by ParadigMS Foundation on .

Neuromyelitis optica spectrum disorder (NMOSD) is a rare but severe neuroinflammatory disease requiring rapid diagnosis and prompt treatment to prevent irreversible disability. In this expert-led webinar, Vincent van Pesch explores the latest advances in NMOSD diagnosis and management, with a particular focus on clinical practice in Belgium. The webinar is introduced and moderated by Melissa Cambron. The session covers diagnostic red flags, imaging features, antibody testing, and evolving therapeutic strategies that are reshaping patient care. Learning Objectives After watching...

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