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Media Category: MRI

Astrocytes and myelin – pathology and pathway

Written by ParadigMS Foundation on .

Advances in antibody testing and biomarker-driven diagnostics have reshaped the distinction between Multiple Sclerosis (MS), Neuromyelitis Optica Spectrum Disorder (NMOSD), and MOG antibody-associated disease (MOGAD). Florian Deisenhammer reviews the historical shift from considering NMO a subtype of MS to recognizing NMOSD as a distinct antibody-mediated condition, and outlines how AQP4-IgG and MOG-IgG testing – together with characteristic MRI and CSF patterns – supports more accurate diagnosis. A central message is that these diseases can overlap clinically, but differ...

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Astrocytes and myelin – Clinical aspects: available and future treatment

Written by ParadigMS Foundation on .

This lecture explains how antibody-mediated pathology translates into clinical phenotypes and treatment strategies in Neuromyelitis Optica Spectrum Disorder (NMOSD) and Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD). Melinda Magyari contrasts the core targets, astrocytes (aquaporin-4) in NMOSD versus myelin/oligodendrocytes (MOG) in MOGAD, and shows how these mechanisms drive differences in relapse recovery, long-term disability, and therapeutic priorities. A major emphasis is placed on early antibody testing to avoid misdiagnosis (particularly as Multiple Sclerosis) and...

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New insights in the 2024 McDonald criteria: imaging biomarkers shaping MS diagnosis

Written by ParadigMS Foundation on .

In this keynote lecture at the Belgian MS Symposium 2025, Pietro Maggi discussed how advanced MRI biomarkers have been integrated into the upcoming 2024 revisions of the McDonald diagnostic criteria for Multiple Sclerosis. Key Insights from the Webinar: These revisions aim to improve diagnostic precision and reduce misdiagnosis, particularly in early or atypical cases. Among the most significant updates are: Optic nerve involvement — now recognized as a fifth anatomical location for demonstrating dissemination in space (DIS), supported by MRI, visual evoked potentials (VEP), and optical...

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MRI & OCT

Written by ParadigMS Foundation on .

30th June 2022, Seventh ParadigMS Symposium During the Seventh Belgian ParadigMS Symposium, Prof Celia Oreja-Guevara and Prof Veronica Popescu had a workshop on MRI & OCT.

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MRI

Written by ParadigMS Foundation on .

08th September 2022, ParadigMS Egypt Symposium ParadigMS Foundation organised, in collaboration with the Egyptian MS Society, a two-day symposium that took place from Thursday 8th September 2022 through Friday 9th September 2022 in Cairo, Egypt. Here you can review the full workshop presentation on MRI. BIOGRAPHY CELIA OREJA-GUEVARA Vice Chair of Neurology and Head of Multiple Sclerosis Center at University Hospital San Carlos, Madrid Professor Celia Oreja-Guevara is Vice Chair of Neurology and Head of Multiple Sclerosis Center at the University Hospital San Carlos, Madrid and Professor...

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MRI & OCT

Written by ParadigMS Foundation on .

30th June 2022, Seventh ParadigMS Symposium  During the Seventh Belgian ParadigMS Symposium, Prof Celia Oreja-Guevara and Prof Veronica Popescu had a workshop on MRI & OCT. This video interview with Prof Veronica Popescu is based on the workshop on MRI & OCT. Consult here the video interview. .embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; } ABSTRACT By the end of this workshop...

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