Welcome to the ParadigMS E-learning Course

This e-learning course has been developed to provide practical guidance on the evolving management of Multiple Sclerosis, with a particular focus on progressive disease.

While significant advances have been achieved in relapsing Multiple Sclerosis, progressive Multiple Sclerosis remains an area of unmet need. Early identification of progression and timely intervention are essential to improve long-term patient outcomes.

This course brings together ParadigMS experts, offering collaborative insight drawn from diverse clinical settings. It reflects an international cross-collaboration, with experts sharing perspectives and experiences across countries and continents to enrich clinical understanding and practice.

Designed as a practice-oriented learning model, it provides actionable guidance and tools that can be directly applied in routine care. Learners will benefit from:

• A deeper understanding of disease progression, including concepts such as PIRA and smouldering disease
• Practical approaches to identifying early signs of progression in clinical practice
• An overview of current and emerging treatment strategies, including early high-efficacy therapies
• Insights grounded in real-world clinical experience from international settings

Whether used for individual learning or within hospital and academic training settings, the course aims to equip neurologists and healthcare professionals with the tools needed to make informed clinical decisions, improve patient outcomes, and adopt a more proactive and evidence-based approach to multiple sclerosis management.

Watch the e-learning teaser by pressing play button, and discover some of the experts behind this e-learning.

Bart Van Wijmeersch  (BE) Associate Professor of Neurology at the University of Hasselt

Carlo Pozzilli  (IT) Professor of Clinical Neuroscience at University of Rome “La Sapienza”

Celia Oreja-Guevara (ES) Vice Chair of Neurology and Head of Multiple Sclerosis Center at the University Hospital San Carlos, Madrid

Melinda Magyari  (DK) Director of the Danish Multiple Sclerosis Registry

Patrick Vermersch  (FR) Vice-president of Research in the fields of Life and Health Sciences at the University of Lille

Tjalf Ziemssen (DE) Professor of Clinical Neuroscience at University Clinic Carl-Gustav Carus in Dresden

Funding

This e-learning has been made possible thanks to an Independent Medical Educational Grant of Sanofi (IME-2024-20396). The Grantor had no influence on the content.