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ParadigMS publication in NEURON(E) journal: Translating the 2024 McDonald Criteria into Clinical Practice 

Source (journal article): NEURON, Vol. 30, #3 (2025), pp. 18–22 (Dutch). In this article, Christine Lebrun-Frenay, member of the McDonald and ECTRIMS committees and co-founder of the RIS Consortium, reviews the rationale behind the 2024 revision and discusses its practical implications, particularly in asymptomatic patients transitioning from Radiologically Isolated Syndrome (RIS) to Multiple Sclerosis (MS). This publication reflects ParadigMS’ ongoing commitment to translating evolving diagnostic frameworks into clinically relevant guidance for neurologists. Key takeaways The...

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ParadigMS Activity Report 2024 – 2025

ParadigMS Activity Summary 2024–2025 Advancing scientific knowledge through publications ParadigMS experts actively contributed to the international scientific literature, co-authoring multiple peer-reviewed publications addressing key clinical challenges. These included comprehensive reviews and position papers on topics such as the management of Multiple Sclerosis in older individuals, progressive MS, generics and biosimilars, and the evolving role of microglia and novel therapeutic targets. These publications reinforced ParadigMS’ commitment to translating scientific evidence...

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Improvement of measured and perceived disability in overweight patients with Multiple Sclerosis trough different patterns of Mediterranean hypocaloric diet.

Authors: Federica Felicetti 1, Serena Ruggieri 2, Ilaria Ruotolo 1, Chiara Livi 1, Giovanni Sellitto 3, Giorgia D’Ambrosi 1, Riccardo Nistri 1, Antonio Ianniello 3, Giovanna Borriello4, Carlo Pozzilli 3, Maria Petracca 5 1MS Center, Sant’Andrea Hospital, Rome, Italy. 2Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy. 3MS Center, Sant’Andrea Hospital, Rome, Italy; Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy. 4MS Center, Neurology Unit, Fatebenefratelli San Pietro Hospital, Rome, Italy. 5Department of Human Neurosciences,...

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