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Media Category: Pregnancy

Multiple Sclerosis and pregnancy: balancing treatment, safety and family planning

Written by ParadigMS Foundation on .

Pregnancy and family planning remain important considerations in the management of Multiple Sclerosis (MS), particularly as treatment options become more effective and diverse. In this expert session, Thomas Berger reviews how different disease-modifying therapies (DMTs) can influence decisions before, during and after pregnancy, and highlights the importance of evidence-based counselling, individualized treatment planning and careful consideration of breastfeeding. Key Insights from the Lecture: Pregnancy itself is not presented as the main risk for women with Multiple Sclerosis;...

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Early intervention in Multiple Sclerosis: the role of high-efficacy therapies in long-term outcomes

Written by ParadigMS Foundation on .

The treatment landscape for Multiple Sclerosis has expanded considerably, providing clinicians with a growing range of disease-modifying therapies. However, an important question remains: should treatment begin with a moderate-efficacy therapy and escalate when disease activity occurs, or should high-efficacy treatment be introduced earlier? This webinar examines the evidence behind both strategies, with a particular focus on the window of opportunity available during the early stages of Multiple Sclerosis. The speakers review how early intervention may influence relapse activity, disability...

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Multiple Sclerosis and pregnancy: from planning to postpartum

Written by ParadigMS Foundation on .

Family planning is a central concern for women living with multiple sclerosis, as the disease often affects patients during their reproductive years. Questions around pregnancy, treatment safety, and postpartum relapse risk require careful, individualized planning. With the right multidisciplinary approach and treatment strategies, pregnancy can be safely managed while minimizing risks for both mother and child. Key Insights from the Lecture: Family planning is a key concern in MS care Pregnancies are not always planned Planning pregnancy reduces risks Multidisciplinary...

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Pregnancy and Lactation in Multiple Sclerosis

Written by ParadigMS Foundation on .

Family planning is a core part of care in Multiple Sclerosis (MS), particularly because many patients are women of reproductive age. This webinar reviews the clinical considerations around conception, pregnancy, postpartum relapse risk, breastfeeding, and treatment selection. It also addresses how disease-modifying therapies can be used before, during, and after pregnancy to support both maternal disease control and informed reproductive decision-making. Learning Objectives After this webinar, participants should be able to: Explain why family planning should be discussed early in...

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Astrocytes and myelin – Clinical aspects: available and future treatment

Written by ParadigMS Foundation on .

This lecture explains how antibody-mediated pathology translates into clinical phenotypes and treatment strategies in Neuromyelitis Optica Spectrum Disorder (NMOSD) and Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD). Melinda Magyari contrasts the core targets, astrocytes (aquaporin-4) in NMOSD versus myelin/oligodendrocytes (MOG) in MOGAD, and shows how these mechanisms drive differences in relapse recovery, long-term disability, and therapeutic priorities. A major emphasis is placed on early antibody testing to avoid misdiagnosis (particularly as Multiple Sclerosis) and...

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B-Cell Clinical aspects: available and future treatment

Written by ParadigMS Foundation on .

In this keynote delivered in Athens, Professor Carlo Pozzilli takes the audience through the past, present and future of anti-CD20 therapies in multiple sclerosis. Starting from the early interferon era and the first monoclonal antibodies, Professor Pozzilli retraces how B-cell depletion moved from a provocative concept to a central pillar of MS management. Drawing on pivotal trials, 10-year extension data and real-world evidence, the discussion adresses why starting high-efficacy therapy early matters, how anti-CD20 agents compare with other high-efficacy options such as natalizumab, and...

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