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Media Category: Innovation

Independent Education in the Age of the Internet and AI – Celia Oreja-Guevara, President of ParadigMS

Written by ParadigMS Foundation on .

In this short video interview, Celia Oreja-Guevara reflects on the challenges facing the new generation of neurologists. In a time when information is instantly accessible online and artificial intelligence is increasingly used, she emphasises the importance of independent medical education and critical thinking. Watch the interview Why is independent medical education especially important in the age of AI and online information? Celia Oreja-Guevara highlights that while today’s generation has rapid access to information, true medical learning requires more than searching online....

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Looking Ahead: A Shared European Vision for ParadigMS

Written by ParadigMS Foundation on .

In this short video interview, Celia Oreja-Guevara, ParadigMS President, shares her vision for the next five years of ParadigMS. Celia outlines an ambition to develop collaborative scientific projects and strengthen the foundation’s presence within the European neurological community. Watch the interview Celia highlights: The ambition to develop a joint European scientific project Strengthening collaboration across countries and specialisations Moving beyond review articles toward more dissemination of original research Publishing work that reflects real clinical practice...

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Building ParadigMS: From Vision to Impact in MS Education – Celia Oreja-Guevara, President of ParadigMS

Written by ParadigMS Foundation on .

In this short video interview, Celia Oreja-Guevara reflects on the early days of ParadigMS and the key milestones achieved during her presidency. She explains how defining clear objectives, building a committed clinical team, and working collaboratively were essential to transforming the organisation into a sustainable educational platform. Watch the interview In the interview, Celia highlights: The importance of clear objectives and strong structure Working collaboratively as clinicians Launching webinars as a key milestone Publishing regular scientific articles Expanding...

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Real-Life Experiences with biosimilars 

Written by ParadigMS Foundation on .

Key takeaways Generics and biosimilars are increasingly relevant in Multiple Sclerosis (MS) as healthcare systems seek cost containment without compromising clinical outcomes. Biosimilars are not identical copies, but are rigorously evaluated to demonstrate high similarity to reference biologics in structure, efficacy, safety, and immunogenicity through the EMA/FDA “totality of evidence” framework. Clinical trials and real-world evidence consistently show comparable efficacy and safety between originator biologics and biosimilars used in MS, including interferon beta, rituximab (off-label),...

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Why ParadigMS? Celia Oreja-Guevara, President of ParadigMS

Written by ParadigMS Foundation on .

In this short video interview, Celia Oreja-Guevara explains why she founded ParadigMS and what continues to drive the foundation today. High-quality education in multiple sclerosis and related demyelinating diseases should be independent, clinically grounded, and shared across borders. Watch the interview What makes ParadigMS different? Pr. Celia Oreja-Guevara describes ParadigMS as a group created by clinicians, for clinicians. Rather than focusing on theory alone, the aim has always been to translate everyday clinical experience into practical education that supports neurologists...

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Sphingosine system – pathology and pathway

Written by ParadigMS Foundation on .

This lecture introduces the sphingosine-1-phosphate (S1P) system as a complex, tightly regulated lipid-signaling pathway with relevance beyond Multiple Sclerosis, extending into vascular biology and other neurological diseases. The speaker explains how S1P is produced and transported, how it acts both intracellularly and via surface receptors, and why its biological effects depend on compartment, binding proteins, and the balance between pro-apoptotic ceramide and pro-survival S1P. The talk also links S1P dysregulation to disease mechanisms and emerging research questions, including...

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FAQs

Is ParadigMS for free?

Yes, a ParadigMS subscription is free for healthcare practitioniers. 

Do subscriptions auto-renew?
Your subscription will automatically renew on yearly basis. If you cancel your plan, it will not renew at the end of your subscription cycle. 
I am a representative from industry, can I subscribe?

Free subscriptions to ParadigMS are reserved for healthcare practitioners. If you are a representative of the industry please contact us on learning@paradigms.foundation and we would advise you how to get the access to the material. 

What happens if I subscribe as a HCP if I am not?
If you subscribe as a healthcare practitioner and it is proven that you are not a healthcare practitioner, we will cancel your subscription immediately. 
I am a patient, can I subscribe?

ParadigMS is designed specifically for healthcare practitioners, with content and language tailored to their professional needs. While patients cannot subscribe directly, we encourage you to consult your healthcare provider for relevant insights and updates that may benefit you.

Why should I subscribe to ParadigMS's e-platform?

Subscribing to ParadigMS’s e-platform gives you access to up-to-date information and valuable learning materials on multiple sclerosis and NMO, along with expert insights and the latest innovations in the field. It’s an essential resource for staying informed and enhancing your knowledge in MS care.

How can I cancel my subscription?
You can cancel your subscription in your account settings. 
Can I financially support ParadigMS?

Yes, you can financially support ParadigMS! We welcome donations to help us continue our mission of advancing multiple sclerosis education and research. Your contribution directly supports the creation of educational resources, expert discussions, and innovative projects in MS care. Visit our donation page to learn more about how you can make a difference: ParadigMS Donate.