Skip to main content

Presentation – MS Genetics

The pathobiology of MS involves a complex interplay of mechanisms that varies over time.

2016, The pathobiology of MS involves a complex interplay of mechanisms that varies over time: Genes, Immune System, Environment. This presentation focuses on the role of genes.


  • Genetic predisposition to MS (hereditary factors)
  • Genetic factors and MS clinical course
  • Genetic factors and effects of therapy of MS (DMT) – pharmacogenetics
  • Possible mechanisms of the regulation of  gene expression in MS

Prof Hans-Peter Hartung, MD, PhD, FRCP, is Professor and Chairman of the Department of Neurology at Heinrich-Heine University, Dusseldorf, Germany. Research Interest: Pathogenesis of autoimmune diseases of the central and peripheral nervous system (MS, GBS, CIDP) and their animal models and design and exploration of experimental therapies. Development of regenerative therapies for inflammatory, ischemic and traumatic insults to the nervous system. Development of new immunomodulatory therapies for MS, GBS, CIDP and identification of biomarkers of diease activity, prognosis, therapeutic response.

Alexei Boyko gained his MD and PhD from the Russian State Medical University, Moscow and has been Professor of the Department of Neurology and Neurosurgery at this university since 1997. He was the Chief Neurologist of the Department of Health Care of the Government of Moscow in 2001-2015, Director of the Moscow Multiple Sclerosis Center in 2004-2014 and Director of the MS Clinical and Research Center of Neuroclinic since 2015, Director of the Neuroimmunological Department of the Federal Center CVPS. Professor Boyko has been a member of the “Oslo International Think-tank on MS Epidemiology, Analytical Approaches to Study of the Aetiology” at the Center for Advanced Studies of the Norwegian Academy of Science and Letters in 1994-1995, and worked at UBC MS Center in 1998 (Vancouver, Canada).



  • Directors

  • Author(s)

    Prof Hans-Peter Hartung and Prof Alexey N. Boyko
  • Country

  • Release Date

    October 06, 2016
  • Views


Educational slide decks
endorsed by experts

Minimum two MS experts collaborate to produce an educational slide deck. These slide decks are presented (live) to ParadigMS members, peer reviewed and updated.
The slide decks are published on the ParadigMS website “on behalf of ParadigMS”.

Consensus publications

Based on the slide decks, publications are produced. These publications are peer reviewed and published as consensus publications.

Regional and national educational events

Regional (fe: Scandinavian countries, Benelux, …) or national events where state-of-the-art science is transferred to general neurologists and other care givers (nurses, etc) that are confronted with MS in their day to day practice.

Web-based educational tools and resources

Webinars can complement the educational events.

Medical education (ME) programs

The educational slide decks, events and webinars can be important building blocks of accredited educational programs.


Do subscriptions auto-renew?
Your subscription will automatically renew on a monthly or yearly basis, depending on the plan you have chosen. If you cancel your plan, it will not renew at the end of your subscription cycle. It will end once the period you have paid for is over.
What happens if I subscribe as a healthcare practitioner if I am not a healthcare practitioner?
If you subscribe as a healthcare practitioner and it is proven that you are not a healthcare practitioner, you will be banned immediately from the community and could be liable to prosecution.
How can I cancel my trial or subscription?
You can cancel your trial or subscription in your account settings. If you cancel during the trial period you will not be charged.

Terms and Conditions

All the Terms and Conditions of the ParadigMS Foundation Website can be downloaded here.