The term ‘Smouldering MS’ is one of the latest concepts that MS researchers are advancing in an attempt to understand and address ongoing clinical deterioration in multiple sclerosis patients despite an apparent absence of focal inflammatory activity (relapse and/or MRI activity).
In a recent review article co-authored by ParadigMS board members Professors Veronica Popescu and Laura Airas, Giovannoni et al. (2022) outline what they believe is driving the pathology underlying smouldering MS. They suggest that current disease-modifying therapies do not adequately treat and manage smouldering MS, and provide insights into what needs to be done to detect and eventually reverse this ongoing neurodegeneration in the brains of MS patients that eventually leads to disability progression.
You can read this paper, which can be downloaded freely from PubMed.
Minimum two MS experts collaborate to produce an educational slide deck. These slide decks are presented (live) to ParadigMS members, peer reviewed and updated.
The slide decks are published on the ParadigMS website “on behalf of ParadigMS”.
Based on the slide decks, publications are produced. These publications are peer reviewed and published as consensus publications.
Regional (fe: Scandinavian countries, Benelux, …) or national events where state-of-the-art science is transferred to general neurologists and other care givers (nurses, etc) that are confronted with MS in their day to day practice.
Webinars can complement the educational events.
The educational slide decks, events and webinars can be important building blocks of accredited educational programs.